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Every guide GutCode has published, in one place—organized by topic so you can find exactly what you are looking for. 220 evidence-based articles on the microbiome, digestive conditions, probiotics, and diet.

220 guides across 15 topics
Gut Health Basics 10 IBD: Crohn's & Ulcerative Colitis 12 IBS & SIBO 29 Leaky Gut & Intestinal Permeability 15 Upper GI & Acid Reflux 20 Gut-Brain Axis 16 Constipation & Motility 10 Liver, Gallbladder & Pancreas 18 Cancer Prevention & Screening 3 Microbiome Testing 5 Food Sensitivities & Allergies 19 Probiotics & Supplements 20 Diet, Fiber & Fermented Foods 13 Metabolic & Hormonal Health 18 Microbiome Science 9

Gut Health Basics

10 guides

IBD: Crohn's & Ulcerative Colitis

12 guides

IBS & SIBO

31 guides
Guide
Best Digestive Enzyme Supplements for Bloating & IBS (2026)
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Best Low-FODMAP Protein Powder for IBS & SIBO (2026)
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Best Peppermint Oil Capsules for IBS & Bloating (2026)
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Bloating: Causes, Types, and Evidence-Based Solutions (2026)
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Fecal Microbiota Transplant (FMT): FDA Approval, C. difficile Cure Rates & Emerging Science
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Food Poisoning & Microbiome Recovery: The Post-Infectious IBS Guide
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IBS (Irritable Bowel Syndrome): Causes, Subtypes, Diet, and Evidence-Based Treatment (2026)
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IBS (Irritable Bowel Syndrome): Subtypes, FODMAP, and What Actually Works (2026)
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IBS Complete Guide: Rome IV Criteria, Low-FODMAP Diet & Microbiome Treatments
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IBS Gut-Brain Connection, Microbiome & Evidence-Based Treatment Guide
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IBS Subtypes: IBS-D, IBS-C, IBS-M & IBS-U — Rome IV Criteria & Treatment Guide
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IBS Treatment Protocol: Gut Motility, Low-FODMAP Diet & Beyond
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IBS Treatment: Low-FODMAP Diet, Rifaximin, Visceral Hypersensitivity — Complete Evidence Guide (2026)
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IBS and the Low-FODMAP Diet: The Evidence-Based Guide (2026)
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IBS, the Gut Microbiome, and the Low-FODMAP Diet: Evidence and Limitations (2026)
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IBS-C: The Gut-Brain-Microbiome Guide — Low FODMAP, Linaclotide & Beyond
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IBS: Low-FODMAP Diet, Rome IV Criteria, and the Evidence for Every Treatment (2026)
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Low FODMAP Diet for IBS: Gibson and Shepherd Monash University Evidence (76% Response Rate), Elimination-Reintroduction Protocol, Why Long-Term Low FODMAP Is Wrong, and the Complete 3-Phase Food Guide (2026)
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Low-FODMAP Diet for IBS: The Evidence-Based Guide (2026)
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Probiotics for IBS: Ford 2014 Meta-Analysis (43 RCTs, NNT=7), Bifidobacterium infantis 35624 (Whorwell 2006), Strain Specificity, CFU Counts, Refrigerated vs Shelf-Stable — Complete Evidence Guide (2026)
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SIBO (Small Intestinal Bacterial Overgrowth): Hydrogen vs Methane Breath Test, Rifaximin Protocol, Elemental Diet, and Prokinetics to Prevent Recurrence (2026)
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SIBO (Small Intestinal Bacterial Overgrowth): The Complete Guide
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SIBO Breath Test, Diagnosis & Treatment Guide: Rifaximin, Elemental Diet & Low-FODMAP
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SIBO Complete Guide: Breath Testing, Rifaximin Protocols & IBS Overlap
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SIBO Complete Guide: Hydrogen, Methane & Breath Testing
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SIBO Guide: Hydrogen vs Methane, Breath Test & Rifaximin Treatment
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SIBO Guide: Symptoms, Testing, and Treatment (2026)
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SIBO Hydrogen Breath Testing & Treatment Guide
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SIBO Treatment Options: Antibiotics, Herbal Protocols, and the Elemental Diet (2026)
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SIBO Treatment Protocol & Diet Guide
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SIBO: Small Intestinal Bacterial Overgrowth — Diagnosis, Rifaximin, and What Actually Works (2026)
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Leaky Gut & Intestinal Permeability

16 guides
Guide
Alcohol and Gut Health: How Drinking Destroys Your Microbiome
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How to Actually Test for Leaky Gut: The 5 Most Reliable Biomarkers
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Intestinal Permeability Science: Tight Junctions, Zonulin & Leaky Gut Explained
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Intestinal Permeability and Leaky Gut: Zonulin Mechanism, Fasano 2012 Science, Tight Junction Proteins Claudin and Occludin, LPS Translocation, and Evidence-Based Repair
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Intestinal Permeability and Leaky Gut: Zonulin, Tight Junctions, Claudin/Occludin Biology, LPS Translocation and Systemic Inflammation
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Leaky Gut & Intestinal Permeability: Tight Junctions, Zonulin & LPS — Complete Science Guide
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Leaky Gut & Intestinal Permeability: Zonulin, Tight Junctions & Autoimmune Disease
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Leaky Gut (Intestinal Permeability): What the Science Actually Says — Causes, Tests, and Fixes (2026)
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Leaky Gut (Intestinal Permeability): Zonulin, Tight Junctions, LPS Endotoxemia, and What the Evidence Says Actually Works to Repair the Barrier (2026)
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Leaky Gut Healing Protocol: Evidence-Based Steps to Restore Intestinal Barrier (2026)
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Leaky Gut Syndrome: Tight Junctions, Zonulin & Evidence-Based Repair Protocol
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Leaky Gut Syndrome: What the Science Actually Says (2026)
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Leaky Gut Testing: Zonulin, Lactulose/Mannitol & Evidence-Based Repair
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Leaky Gut and Intestinal Permeability: Fasano 2000 Zonulin Discovery, Tight Junction Proteins (Claudin, Occludin, ZO-1), LPS Translocation and Systemic Inflammation, Lactulose:Mannitol Ratio Testing, and Evidence-Based Gut Barrier Repair (2026)
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Leaky Gut and Intestinal Permeability: Zonulin, Tight Junctions, Science vs. Hype (2026)
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Does L-Glutamine Help Leaky Gut? Evidence, Dosing & Best Supplements (2026)
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Upper GI & Acid Reflux

20 guides
Guide
Barrett's Esophagus: GERD to Adenocarcinoma — Treatment, Surveillance & Microbiome Guide
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Guide
Eosinophilic Esophagitis (EoE): Food Elimination Diet, Diagnosis & Treatment Guide
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Eosinophilic Esophagitis: Food Triggers, Elimination Diets & Dupilumab Guide
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Eosinophilic Gastroenteritis: Food Allergy Triggers, Elimination Diet & Dupilumab Guide
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Functional Dyspepsia: PDS vs EPS, Rome IV, and Evidence-Based Treatment Guide
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GERD & Acid Reflux: LES Dysfunction, PPIs, and the Evidence-Based Diet Guide
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GERD Complete Science Guide: LES, PPIs, Diet & Microbiome
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GERD and Acid Reflux: What PPIs Don't Fix (And What Actually Does)
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Gastroparesis & Delayed Gastric Emptying: Vagus Nerve, Diet & Prokinetic Guide
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Gastroparesis: Delayed Gastric Emptying — Causes, Diagnosis & Treatment Guide
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H. Pylori Eradication Guide: Triple Therapy, Resistance & Recovery
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H. Pylori: Causes, Treatment, Probiotics, and Eradication (2026)
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H. Pylori: Symptoms, Testing, and How to Eradicate It (2026)
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H. pylori Eradication: Triple Therapy, Bismuth & Microbiome Recovery
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H. pylori: CagA Virulence Factor (IARC Group I Carcinogen, 10-15× Gastric Cancer Risk), Clarithromycin Resistance Rates Exceeding 20%, Bismuth Quadruple Therapy as New First-Line, Stool Antigen vs Urea Breath Test, Probiotic Adjunct (Ojetti 2012: 72→84% Eradication), and How to Test-and-Treat (2026)
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H. pylori: CagA Virulence Factor and Gastric Cancer Risk, Urea Breath Test Diagnosis, Triple vs Bismuth Quadruple Therapy, and Probiotic Adjuncts
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H. pylori: How Barry Marshall Won the Nobel Prize by Drinking Bacteria, Urease Acid Neutralization, CagA Virulence Factor, Triple Therapy Eradication Protocol, and 10× Gastric Cancer Risk Reduction After Treatment (2026)
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H. pylori: Survival, Eradication & Microbiome Recovery Guide
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H. pylori: The Bacteria Living in Half the World's Stomachs (And How to Get Rid of It)
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Peptic Ulcer & H. pylori: Triple Therapy, Resistance & the Diet Evidence
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Gut-Brain Axis

16 guides
Guide
Gut-Brain Axis: How Your Microbiome Affects Mood, Anxiety, and Cognition (2026)
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Gut-Brain Axis: How Your Microbiome Controls Brain Function & Mental Health
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Gut-Brain Axis: Vagus Nerve Signaling, Enteric Nervous System, 95% of Serotonin Made in the Gut, Psychobiotics Evidence, and Whether Probiotics Can Actually Treat Anxiety and Depression
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Gut-Brain Axis: Vagus Nerve, 95% of Serotonin Made in the Gut, Psychobiotics, and How Your Microbiome Shapes Mood, Anxiety, and Cognition (2026)
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Gut-Brain Axis: Vagus Nerve, Enteric Nervous System (100 Million Neurons), 90-95% of Serotonin in the Gut, Psychobiotics Evidence (Dinan/Cryan), and Four Pathways Linking Gut Microbiome to Brain Function (2026)
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Gut-Brain Axis: Vagus Nerve, Serotonin & Microbiome Guide
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Gut-Brain Axis: Vagus Nerve, Serotonin & Psychobiotics — Complete Science Guide
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The Gut-Brain Axis Explained: Why Your Gut Controls Your Mood
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The Gut-Brain Axis: 95% of Serotonin Is Made in Your Gut (2026)
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The Gut-Brain Axis: How Your Microbiome Affects Mood, Anxiety, and Cognition (2026)
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The Gut-Brain Axis: How Your Microbiome Controls Anxiety, Mood, and Mental Health
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The Gut-Brain Axis: How Your Microbiome Controls Your Mood, Anxiety, and Cognition
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The Gut-Brain Axis: Vagus Nerve, Serotonin, and How Your Microbiome Controls Your Mood (2026)
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The Gut-Brain Connection: What the Science Says
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Tryptophan Metabolism: Serotonin vs Kynurenine Pathway Competition, IDO1 and TDO2 Enzymes, Gut Enterochromaffin Cell 5-HT Production, Lactobacillus Indole Signaling, Aryl Hydrocarbon Receptor, and the Gut-Brain Axis Tryptophan Connection
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Vagus Nerve & Gut-Brain Axis: Polyvagal Theory, HRV & Microbiome
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Constipation & Motility

10 guides

Liver, Gallbladder & Pancreas

18 guides
Guide
Bile Acid Malabsorption: Causes, Diagnosis & Cholestyramine Treatment
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Guide
Bile Acids & Gut Microbiome: FXR, TGR5 & Secondary Bile Acids Explained
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Bile Acids & Gut Microbiome: Secondary Bile Acids, FXR/TGR5 Signaling & Cardiovascular Risk
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Bile Acids and the Gut Microbiome: Gut Bacteria Convert Primary Bile Acids (Cholic, Chenodeoxycholic) Into Secondary Bile Acids (DCA, LCA, UDCA) via Deconjugation and 7α-Dehydroxylation, FXR and TGR5 Bile Acid Receptors Control Metabolism and Immunity, TUDCA as Neuroprotective, and Why Microbiome Dysbiosis Raises Colon Cancer Risk via DCA Accumulation (2026)
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Bile Acids: Primary vs Secondary, FXR and TGR5 Receptor Signaling, Gut Microbiome Transformation, UDCA, NASH Bile Acid Dysbiosis, Colorectal Cancer Risk, and the Enterohepatic Circulation
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Digestive Enzymes Guide: Lipase, Protease, Amylase & Malabsorption
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Digestive Enzymes: The Complete Guide
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Digestive Enzymes: Who Needs Them, What They Do, and Which Forms Work (2026)
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Exocrine Pancreatic Insufficiency: Causes, Symptoms, PERT with Creon & Fat Malabsorption Guide
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Exocrine Pancreatic Insufficiency: Digestive Enzymes, Fat Malabsorption & EPI Guide
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Gallbladder & Gallstones: The Complete Guide to Prevention, Treatment & Post-Surgery Diet
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Gallbladder & Gut Health: How Bile Acids Shape Your Microbiome
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Gallbladder Health: Bile, Stones, and the Gut Connection Most Doctors Don't Discuss
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Liver Fibrosis & Cirrhosis Guide: NAFLD to NASH Progression, FIB-4 Score & Reversal
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NAFLD & the Gut Microbiome: How Gut Dysbiosis Drives Fatty Liver (and How to Reverse It)
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NAFLD/MASLD Reversal Guide: Diet, Exercise & Science-Backed Protocols
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Pancreatic Cancer Risk Factors, Diet & Microbiome: Early Detection Guide
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Pancreatic Exocrine Insufficiency: Enzymes, Fat Malabsorption & Evidence-Based Supplementation
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Cancer Prevention & Screening

3 guides

Microbiome Testing

5 guides

Food Sensitivities & Allergies

19 guides
Guide
A1 vs A2 Casein: Why Dairy Causes Gut Inflammation (It's Not the Lactose)
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Candida Overgrowth in the Gut: What the Evidence Actually Shows
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Candida Overgrowth: Separating Real Science From Wellness Mythology
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Candida Overgrowth: Separating Real Science from Wellness Industry Myths (2026)
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Celiac Disease & Gluten Sensitivity: tTG-IgA, Gut Barrier & Complete Guide
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Celiac Disease: Diagnosis, Gluten Biology, and the Strict Gluten-Free Diet (2026)
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Celiac Disease: Gluten, Villous Atrophy & the Zonulin Cascade
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Celiac Disease: HLA-DQ2/DQ8 Genetics, Diagnosis & Gluten-Free Treatment Guide
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Celiac Disease: How Gluten Destroys Your Gut Lining & How to Heal
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Elimination Diet & Food Sensitivity Guide: The Complete Low-FODMAP Protocol
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Elimination Diet Protocol for Food Sensitivities: IgG Testing, Reintroduction & Trigger Foods
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Histamine Intolerance & Low-Histamine Diet Guide
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Histamine Intolerance: DAO Deficiency, Low-Histamine Diet, and What Actually Causes Symptoms (2026)
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Histamine Intolerance: DAO Enzyme Deficiency, Gut Connection & Low-Histamine Diet Protocol
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Histamine Intolerance: DAO Enzyme Deficiency, High-Histamine Foods to Avoid, Low-Histamine Diet Protocol, and MCAS vs HIT Distinction (2026)
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Histamine Intolerance: DAO Enzyme Deficiency, Mast Cell Activation, Diamine Oxidase Genetics, Low-Histamine Diet Science, and the Gut Microbiome Connection
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Histamine Intolerance: Symptoms, Causes, and the Low-Histamine Diet (2026)
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Oxalate Sensitivity, Kidney Stones, and Gut Health: The Oxalobacter Connection (2026)
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Oxalates & the Gut Microbiome: Oxalobacter formigenes, Kidney Stones & Low-Oxalate Diet Guide (2026)
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Probiotics & Supplements

23 guides
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Align vs Culturelle: Which Daily Probiotic Actually Works Better? (2026)
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Best Digestive Bitters for Bloating & Sluggish Digestion (2026)
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Best Fiber Supplements for Gut Health (2026) — Science-Ranked
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Best Postbiotic Supplements 2026: Butyrate, Tributyrin & Urolithin A Compared
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Best Probiotics for IBS: What the Clinical Trials Actually Show — GutCode
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Best Probiotics for SIBO & Gut Repair (2025) — GutCode
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Best Probiotics for Men (2026): Science-Ranked by Strain
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Best Probiotics for Women (2026): Science-Ranked by Strain
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Best Probiotics: What the Science Actually Says
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Best Saccharomyces Boulardii Probiotic Brands for Antibiotic-Associated Diarrhea (2026)
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Garden of Life vs Thorne Probiotic: An Evidence-Based Comparison — GutCode
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Postbiotics: The Complete Guide to Butyrate, Urolithin A & SCFAs
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Prebiotic Fiber and Microbiome Diversity: What to Eat and Why It Matters (2026)
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Prebiotics vs Probiotics: What's the Difference and Do You Need Both? (2026)
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Probiotic Strain Specificity: LGG −60% Antibiotic-Associated Diarrhea (Doron 2011 Meta, N=4,780), S. boulardii for C. diff and Traveler's Diarrhea, VSL#3 in IBS-D, BB-12 for Immunity, L. reuteri DSM 17938 for Infant Colic — Why Strain Identity Matters More Than CFU Count (2026)
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Probiotic Strains: Which Ones Have RCT Evidence for What (2026)
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Probiotics for Immune Health: What the Evidence Actually Shows (2026)
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Probiotics vs Prebiotics: What's Actually Different & Which One You Need
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Probiotics vs Prebiotics: What's the Difference and Which Do You Need?
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Seed DS-01 vs Ritual Synbiotic: Which Is Worth the Price?
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Seed vs Garden of Life vs Thorne Probiotic: Which Is Actually Worth It? (2026)
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Seed vs Ritual vs Garden of Life vs Thorne: Probiotic Brands Compared (2026)
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Soil-Based vs Lactobacillus Probiotics: Which Type Works Better?
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Diet, Fiber & Fermented Foods

13 guides
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Butyrate & Short-Chain Fatty Acids: The Complete Gut Health Guide
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Butyrate & Short-Chain Fatty Acids: The Complete Gut Health Guide
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Butyrate and Gut Health: Primary Fuel for Colonocytes, HDAC Inhibition, Faecalibacterium prausnitzii as Key Producer, Resistant Starch as Preferred Substrate, Colorectal Cancer Prevention Mechanism, and Sodium Butyrate vs Tributyrin vs Diet (2026)
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Circadian Rhythm and the Gut Microbiome: BMAL1/CLOCK Genes, How Gut Bacteria Oscillate With the Host, Time-Restricted Eating Effects on Microbiome Composition, and the Dysbiosis-Jetlag Connection
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Dietary Fiber, Gut Microbiome, and Butyrate: The Complete Science (2026)
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Foods That Destroy Your Gut Microbiome
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Gut Microbiome Diversity: Fiber, Fermented Foods, Akkermansia & Butyrate Guide
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Gut Microbiome Diversity: Wastyk 2021 Fermented Food Trial, 30 Plants Per Week, Prebiotics vs Probiotics — Complete Evidence Guide (2026)
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Intermittent Fasting and the Gut Microbiome: Circadian Oscillations (Thaiss 2014 Cell), TRE Increases Akkermansia and SCFA Producers, Wilkinson 2020 10-Hour TRE in Metabolic Syndrome, and How to Time Eating for Microbiome Health (2026)
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Intermittent Fasting and the Gut Microbiome: What Fasting Does to Your Bacteria (2026)
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Polyphenols and the Gut Microbiome: Urolithins from Pomegranate Ellagitannins (Amazentis ATLAS Trial — Urolithin A 500mg +12% Mitophagy Markers), Equol from Soy Daidzein (Only 30–50% People Produce It), Gut Biotransformation of Resveratrol, Quercetin, and Anthocyanins — Why You're Only as Good as Your Microbiome's Ability to Transform What You Eat (2026)
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Short-Chain Fatty Acids: Butyrate as HDAC Inhibitor, Propionate GPR41/43 Signaling, Acetate Brain Fuel
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Short-Chain Fatty Acids: Butyrate, Propionate, and Acetate — Microbiome Fermentation of Dietary Fiber, Colonocyte Fuel, HDAC Inhibitor Mechanisms, GPR41/GPR43 Signaling, and Gut Barrier Protection
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Metabolic & Hormonal Health

18 guides
Guide
70% of Your Immune System Lives in Your Gut: The Science
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Akkermansia Muciniphila: The Gut Barrier Bacterium
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Akkermansia Muciniphila: The Gut Barrier Bacterium That Changes Everything
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Akkermansia muciniphila: Amuc_1100 Outer Membrane Protein, TLR2 Signaling, Pasteurized vs Live Bacteria (Plovier 2017), First Human RCT (Depommier 2019), Mucin Degradation Biology, and How to Increase It
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Akkermansia muciniphila: Mucin Layer Biology, Everard 2013 Obesity Mouse Model, Plovier 2017 Pasteurized Form & Why Metformin Increases It
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Akkermansia muciniphila: The Gut Barrier Bacterium and Its Role in Metabolic Health (2026)
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Akkermansia muciniphila: The Gut Barrier Bacterium — Everard 2013, Plovier 2017 Pasteurized vs Live, Amuc_1100 Protein, 3-7% of Healthy Microbiome, Lower in Obesity and Diabetes, and How to Increase It With Polyphenols, Omega-3, and Caloric Restriction (2026)
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Fecal Microbiota Transplant (FMT): FDA-Approved C. diff Cure, 90% Success Rate & What the Science Says
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Gut Health and Hormones: The Estrobolome, PCOS, and Estrogen Dominance (2026)
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Gut Microbiome & Obesity: The Firmicutes-Bacteroidetes Science Explained
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Gut Microbiome & Weight Loss: Firmicutes, Bacteroidetes & Akkermansia Science Guide
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Gut Microbiome and Type 2 Diabetes: How Bacteria Influence Blood Sugar
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Gut Microbiome and Weight Loss: What the Science Actually Shows
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Gut Microbiome and Weight Loss: What the Science Actually Shows (2026)
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Gut-Skin Axis: How Your Microbiome Affects Acne, Eczema, and Rosacea (2026)
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Gut-Skin Axis: How Your Microbiome Affects Acne, Eczema, and Rosacea (2026)
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Short Bowel Syndrome & Intestinal Failure: Complete Nutrition Guide
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Vitamin D: VDR Nuclear Receptor Mechanism, Holick Deficiency Data, T-Cell Immune Modulation, 25(OH)D Testing, and Why Supplementation Dose Matters
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Microbiome Science

9 guides